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Missing
a good night's sleep could increase your risk for ulcers. Medical scientists in Britain
found an ulcer-fighting protein pro-duced by the stomach and small intestine is most
prevalent at night and suppressed after a meal. High levels of this chemical, TFF2, are
found around breaches in the gut lining, such as those caused by ulcers. Investigators
believe this protein triggers the repair of tissue damage. The physicians studied 12
healthy non-smokers, ages 20 to 24, for 24 hours. The volunteers all ate early or
mid-afternoon, went to bed at 11:30 p.m., and were asleep by 1 a.m. Samples of their
digestive juices were collected every two hours during the study. TFF2 levels were highest
after 1 a.m., peaking at 5 a.m. The levels of the healing protein were lowest during the
afternoon and after meals. The researchers conclude that inactivity or sleep is when TFF2
secretion is most active. They reported their findings in the journal Gut.
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